Review



hek-cng-cb2  (Codex Biosolutions)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Codex Biosolutions hek-cng-cb2
    Hek Cng Cb2, supplied by Codex Biosolutions, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hek-cng+cb2/hek+cng+parental+cell+line/pm39265249-609-7-13
    Average 90 stars, based on 1 article reviews
    hek-cng-cb2 - by Bioz Stars, 2026-10
    90/100 stars

    Images

    Related Articles

    other:

    Article Title: The multicomponent Passerini reaction as a means of accessing diversity in structure, activity and properties: Soft and hard vanilloid/cannabinoid modulators.
    Article Snippet: The HEK-CNG parental cell line, HEK-CNG-CB1 and HEK-CNG-CB2 cell lines were purchased from Codex BioSolutions, Inc. HEK-CNG cells were cultured in DMEM with 10 % FBS, 1 % P/S, and 25 mg/ml G418 at 37 ◦C and 5 % CO2.

    Article Title: Synthesis and biological evaluation of a ring analogs of the selective CB2 inverse agonist SMM-189
    Article Snippet: Microglia are the principle cell type driving sustained neuroinflammation in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Multiple Sclerosis.. Interestingly, microglia locked into a chronic M1 proinflammatory phenotype significantly up-regulate the cannabinoid receptor 2 (CB2) expression.. Our approach to exploiting CB2 as a therapeutic target in neuroinflammatory diseases focuses on the development of selective CB2 inverse agonists to shift microglia bias to a M2 pro-wound healing phenotype.



    Similar Products

    hek-cng-cb2  (Codex Biosolutions)
    90
    Codex Biosolutions hek-cng-cb2
    Hek Cng Cb2, supplied by Codex Biosolutions, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hek-cng+cb2/hek+cng+parental+cell+line/pm39265249-609-7-13
    Average 90 stars, based on 1 article reviews
    hek-cng-cb2 - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    hek-cng + cb2 (human  (Codex Biosolutions)
    90
    Codex Biosolutions hek-cng + cb2 (human
    Hek Cng + Cb2 (Human, supplied by Codex Biosolutions, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hek-cng+cb2/hek+cng+parental+cell+line/10__1016_slash_j__bmc__2021__116035-384-8-22
    Average 90 stars, based on 1 article reviews
    hek-cng + cb2 (human - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    hek-cng+cb2  (Codex Biosolutions)
    90
    Codex Biosolutions hek-cng+cb2
    (A) Functional activities of SMM-295 in the <t>CB2</t> ACTOne assay (open circles), CB1 ACTOne assay (open triangles), and parental ACTOne cells containing only the <t>CNG</t> ion channel (filled squares). The functional activation of CB2 by the internal control (CP 55,940; filled diamonds) is shown. (B) Western blot analysis of signaling proteins after brief exposure (15 minutes) to SMM-295 in rat NRK-52E proximal tubule epithelial cells. Activation of prosurvival Akt/PKB and MAPK (ERK1/2 and p38) was detected using specific antibodies. β-actin was used as a loading control. ERK1/2, extracellular signal–regulated kinase 1/2.
    Hek Cng+Cb2, supplied by Codex Biosolutions, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/hek-cng+cb2/hek+cng+parental+cell+line/pmc05774215-201-9-14
    Average 90 stars, based on 1 article reviews
    hek-cng+cb2 - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Functional activities of SMM-295 in the CB2 ACTOne assay (open circles), CB1 ACTOne assay (open triangles), and parental ACTOne cells containing only the CNG ion channel (filled squares). The functional activation of CB2 by the internal control (CP 55,940; filled diamonds) is shown. (B) Western blot analysis of signaling proteins after brief exposure (15 minutes) to SMM-295 in rat NRK-52E proximal tubule epithelial cells. Activation of prosurvival Akt/PKB and MAPK (ERK1/2 and p38) was detected using specific antibodies. β-actin was used as a loading control. ERK1/2, extracellular signal–regulated kinase 1/2.

    Journal: The Journal of Pharmacology and Experimental Therapeutics

    Article Title: Selective Cannabinoid 2 Receptor Stimulation Reduces Tubular Epithelial Cell Damage after Renal Ischemia-Reperfusion Injury

    doi: 10.1124/jpet.117.245522

    Figure Lengend Snippet: (A) Functional activities of SMM-295 in the CB2 ACTOne assay (open circles), CB1 ACTOne assay (open triangles), and parental ACTOne cells containing only the CNG ion channel (filled squares). The functional activation of CB2 by the internal control (CP 55,940; filled diamonds) is shown. (B) Western blot analysis of signaling proteins after brief exposure (15 minutes) to SMM-295 in rat NRK-52E proximal tubule epithelial cells. Activation of prosurvival Akt/PKB and MAPK (ERK1/2 and p38) was detected using specific antibodies. β-actin was used as a loading control. ERK1/2, extracellular signal–regulated kinase 1/2.

    Article Snippet: Human embryonic kidney (HEK)–cyclic nucleotide gated (CNG), HEK-CNG+CB1, and HEK-CNG+CB2 cells were obtained from Codex BioSolutions.

    Techniques: Functional Assay, Activation Assay, Western Blot